Measuring of free endotoxin in alum-precipitated vaccine of haemorrhagic septicaemia by limulus amebocyte lysate test
نویسندگان
چکیده مقاله:
Haemorrhagic septicaemia (HS) vaccine which is prepared in Razi Institute is used in endemic areas ofIran. Aluminum-hydroxide gel was used as adjuvant for preparing this vaccine. Post-vaccinal shock reactionswere the main complaint after use of this vaccine. In a previous study, we could improve the vaccine byalum-precipitation Pasteurella multocida cells and removing the liquid phase. In this study, the amount offree endotoxin in aluminum-hydroxide and alum-HS vaccines was determined. It was found that endotoxinlevel was considerably decreased from 0.22 EU/ml to 0.03 EU/ml after alum-precipitation.
منابع مشابه
measuring of free endotoxin in alum-precipitated vaccine of haemorrhagic septicaemia by limulus amebocyte lysate test
haemorrhagic septicaemia (hs) vaccine which is prepared in razi institute is used in endemic areas ofiran. aluminum-hydroxide gel was used as adjuvant for preparing this vaccine. post-vaccinal shock reactionswere the main complaint after use of this vaccine. in a previous study, we could improve the vaccine byalum-precipitation pasteurella multocida cells and removing the liquid phase. in this ...
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عنوان ژورنال
دوره 8 شماره 1
صفحات 83- 85
تاریخ انتشار 2007-03-30
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